NUCLEIC ACID AMPLIFICATION-BASED DETECTION METHODS FOR SARS-COV-2 VARIANT DETECTION: RESEARCH PROGRESS REVIEW

Nucleic acid amplification-based detection methods for SARS-CoV-2 variant detection: research progress review

The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to spread worldwide.SARS-CoV-2 is prone to mutation, resulting in variants with increased transmissibility, pathogenicity, and immune escape capabilities, posing a significant global threat.To effectively monitor new c

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Overexpression of melanocortin 2 receptor accessory protein 2 (MRAP2) in adult paraventricular MC4R neurons regulates energy intake and expenditure

Objective: Melanocortin 2 receptor accessory protein 2 (MRAP2) has a critical role in energy homeostasis.Although MRAP2 has been shown to regulates a number of GPCRs involved in metabolism, the key neurons responsible for the phenotype of gross obesity in MRAP2 deficient animals are unclear.Furthermore, to date, all the murine MRAP2 models involve

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In vitro and in vivo evaluation of biologically synthesized silver nanoparticles for topical applications: effect of surface coating and loading into hydrogels

Aml I Mekkawy,1 Mohamed A El-Mokhtar,2 Nivien A Nafady,3 Naeima Yousef,3 Mostafa A Hamad,4 Sohair M El-Shanawany,5 Ehsan H Ibrahim,5 Mahmoud Elsabahy5–8 1Department of Pharmaceutics and Clinical Pharmacy, Faculty of Pharmacy, Sohag University, Sohag, 2Department of Microbiology and Immunology, Faculty of Medicine, 3Department of Botany and Mi

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